Pain is one of the most common causes for seeking medical attention and immediate relief, and is often associated with limitations in mobility and daily activities and a reduction in quality of life.
In Greece, people with rheumatic diseases amount to about 3.000.000 people. In the total adult Greek population 13% suffer from OA and 2% from inflammatory rheumatic diseases.
Existing treatments do not always adequately meet the basic needs of these patients such as Satisfactory analgesic action and reduction of inflammation and stiffness.
The use of NSAIDs is widespread in the adult population and in fact 70% of people over the age of 65 use NSAIDs at least once a week. However, the use of NSAIDs carries a significant risk of serious gastrointestinal, cardiovascular and renal side effects.
Libytec Pharmaceuticals has developed PEAforce an innovative combination designed specifically to effectively and safely meet the needs of patients with pain such as musculoskeletal disorders, OA, PA.
The combination of its contained ingredients is unique and can offer strong analgesic, neuroprotective, chondroprotective and anti-inflammatory action and action on the endocannabinoid system.
PEAforce contains
PEA (Palmitoylethanolamide) 300mg, Boswellia Serrata 60mg, Curcuma longa radix 95% 100mg, Magnesium 100mg, Pepper nigrum 95% 10mg, Vitamin B1 1,1mg Vitamin B2 1,4mg Vitamin B6 1,4mg Vitamin B12 2,5mcg, L-cysteine 100mg.
Palmitoylethanolamide (PEA) is an endogenous lipid mediator that acts on the endocannabinoid system by directly or indirectly targeting different metabolic pathways. PEA administration can be beneficial in pain and inflammation.
It has been shown to have neuroprotective, anti-inflammatory, and analgesic properties. Often in people with chronic disorders, the body does not produce enough PEA, which causes problems.
A great advantage of PEA is that it is a safe, non-addictive substance that does not cover the pain, but aims to remove the cause. PEA can be taken by anyone suffering from painful disorders, even if they are taking medication, to enhance the effectiveness of the medications being taken.
Curcumin is a molecule that has been shown to have anti-inflammatory, antioxidant, healing and antimicrobial effects. Unlike synthetic drugs, it acts on multiple inflammatory metabolic pathways to help the body return to a normal balance. In addition, curcumin has specialized and unique mechanisms of action that make it invaluable for the treatment of painful diseases.
Curcumin has been found that
- Suppresses the activation of NF-kB, preventing the intensification of inflammation and pain, as well as the breakdown of cartilage
- Inhibits the action of TNF, a major mediator of inflammation
- Reduces COX-2 and inhibits 5-LOX, enzymes responsible for inflammation
The result is that the degradation of cartilage is slowed down and that curcumin has a positive effect on the degenerative inflammatory process in the joints, which is observed in rheumatoid arthritis and osteoarthritis.
Piperine when combined with curcumin, increases its bioavailability by 2.000%.
Boswellic acids (AKBA) are active in various diseases such as osteoarthritis and rheumatoid arthritis. The most commonly used treatments for osteoarthritis include NSAIDs and analgesics. Although these are effective interventions, they do not affect the metabolic pathway of 5-LOX.
The suppression of the synthesis of 5-LOX by bosvelic acids is considered as the main mechanism for their anti-inflammatory action. The pharmacological action of AKBA includes
- Anti-inflammatory action
- Chondroprotective action
- Anabolic effect on cartilage
B vitamins are a class of water-soluble vitamins that play an important role in cell metabolism. They are important for maintaining normal neurological functions. Deficiency in B vitamins can cause pain and inflammation.
Magnesium plays an essential role in regulating energy and the functioning of the nervous and muscular systems. Low magnesium intake is associated with worsening of pain and function and is considered an important risk factor for the development and progression of osteoarthritis.
L-cysteine is a major source of various antioxidants such as glutathione (GSH), glutathione peroxidase, N-acetylcysteine (NAC) and α-lipoic acid.
PEAforce is therefore an innovative unique combination that can provide effective and safe coverage of the needs of patients with painful disorders by adequately meeting their basic needs such as
- Rapid and effective treatment of pain and inflammation
- Reduction of stiffness
- Improving mobility
- Possibility of co-administration with other treatments
- Possibility of longer duration of NSAIDs
- Good tolerance
- Improving the quality of life
| Brand | Libytec |
|---|---|
| Availability | 1-3 business days |
| Flammable | Νο |
| Vegan | No |
| Off from Original Retail Price | 15 |
| Audience | Women, Men |
| Content | 20 δισκία |
| Ages | All |
| Skin Types | All |
PEA (Palmitoylethanolamide) 300mg,
Boswellia Serrata 60mg,
Curcuma longa radix 95% 100mg,
Magnesium 100mg,
Piper nigrum 95% 10mg,
Vitamin B1 1,1mg
Vitamin B2 1,4mg
Vitamin B6 1,4mg Vitamin B12 2,5mcg,
L-cysteine 100mg.
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